Product Name :
2′,7′-Dichlorofluorescein diacetate (CAS 2044-85-1)
Synonym :
Diacetyldichlorofluorescein; DCFDA
Application :
2′,7′-Dichlorofluorescein diacetate is a cell-permeable fluorogenic ROS probe
CAS:
2044-85-1
Purity:
≥95%
Molecular Weight:
485.27
Formula :
C24H14Cl2O7
Physical state:
Solid
solubility :
Soluble in DMSO and acetone. Insoluble in water.
Shipping Condition :
Store at -20° C
Melting point:
232-234° C (lit.)
SMILES:
CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=CC=CC=C5C(=O)O4)Cl)OC(=O)C)Cl
References:
:Are synapses targets of nanoparticles? | Fedorovich, SV., et al. 2010. Biochem Soc Trans. 38: 536-8. PMID: 20298217Characterization of primary cultures of cholesteatoma-associated fibroblasts. | Barbara, M., et al. 2012. Otol Neurotol. 33: 988-95. PMID: 22772001MicroRNAs and reactive oxygen species: are they in the same regulatory circuit? | Jaksik, R., et al. 2014. Mutat Res Genet Toxicol Environ Mutagen. 764-765: 64-71. PMID: 24051449Hypoxia enhances antitumor activity of dichloroacetate. | Kolesnik, DL., et al. 2014. Exp Oncol. 36: 231-5. PMID: 25537215Free p-Cresol Alters Neutrophil Function in Dogs. | Bosco, AM., et al. 2016. Artif Organs. 40: 480-8. PMID: 26496142Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway.Apixaban Formula | Zhou, Y., et al.Price of 874-20-4 2018.PMID:33660360 Cancer Med. 7: 4012-4022. PMID: 29989329Andrographis paniculata and Its Bioactive Diterpenoids Against Inflammation and Oxidative Stress in Keratinocytes. | Mussard, E., et al. 2020. Antioxidants (Basel). 9: PMID: 325604494-Hydroxyhalcone effects on cisplatin-induced genotoxicity model. | Nazari, A., et al. 2021. Toxicol Res (Camb). 10: 11-17. PMID: 33613968N-Acetyl cysteine improves cellular growth in respiratory-deficient yeast. | Chapela, SP., et al. 2022. Braz J Microbiol. 53: 791-794. PMID: 35122656In-vitro toxicity assessment of Eucalyptus robusta Smith extracts via whole-cell bioreporter. | Jin, N., et al. 2022. Ecotoxicol Environ Saf. 240: 113704. PMID: 35653968Visible-Light-Driven Antimicrobial Activity and Mechanism of Polydopamine-Reduced Graphene Oxide/BiVO4 Composite. | Li, B., et al. 2022. Int J Mol Sci. 23: PMID: 35887058Puerarin prevents calcium oxalate crystal-induced renal epithelial cell autophagy by activating the SIRT1-mediated signaling pathway. | Jing, GH., et al. 2022. Urolithiasis. 50: 545-556. PMID: 35913552Pinoresinol diglucoside ameliorates H/R-induced injury of cardiomyocytes by regulating miR-142-3p and HIF1AN. | Wei, Y., et al. 2022. J Biochem Mol Toxicol. 36: e23175. PMID: 35962614A microplate-based DCFH-DA assay for the evaluation of oxidative stress in whole semen. | Benedetti, S., et al. 2022. Heliyon. 8: e10642. PMID: 36158085In vivo effects of chromium. | Witmer, C., et al. 1994. Environ Health Perspect. 102 Suppl 3: 169-76. PMID: 7843092