Product Name :
2-Hydroxyisocaproic acid (CAS 498-36-2)
Synonym :
2-Hydroxy-4-methylvaleric acid; DL-leucic acid
Application :
CAS:
498-36-2
Purity:
99%
Molecular Weight:
132.16
Formula :
C6H12O3
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
78-80° C (lit.)
SMILES:
CC(C)CC(C(=O)O)O
References:
:2-Hydroxyisocaproic acid (HICA): a new potential topical antibacterial agent. | Sakko, M., et al. 2012. Int J Antimicrob Agents. 39: 539-40. PMID: 224835612-hydroxyisocaproic acid is fungicidal for Candida and Aspergillus species. | Sakko, M., et al. 2014. Mycoses. 57: 214-21. PMID: 24125484Antimicrobial 2-hydroxyisocaproic acid and chlorhexidine resist inactivation by dentine. | Sakko, M., et al. 2016. Int Endod J. 49: 352-60. PMID: 259445602-Hydroxyisocaproic acid is bactericidal in human dental root canals exvivo. | Sakko, M., et al. 2017. Int Endod J. 50: 455-463. PMID: 27004733Antifungal sourdough lactic acid bacteria as biopreservation tool in quinoa and rice bread. | Axel, C., et al. 2016. Int J Food Microbiol. 239: 86-94. PMID: 27236463Identification of 2-hydroxyisocaproic acid production in lactic acid bacteria and evaluation of microbial dynamics during kimchi ripening. | Park, B., et al. 2017. Sci Rep. 7: 10904. PMID: 28883404Cytotoxicity and Genotoxicity of a New Intracanal Medicament, 2-hydroxyisocaproic Acid-An InVitro Study. | Selis, D., et al. 2019. J Endod. 45: 578-583. PMID: 30879773Antimicrobial properties of Pediococcus acidilactici and Pediococcus pentosaceus isolated from silage. | Fugaban, JII., et al. 2022. J Appl Microbiol. 132: 311-330. PMID: 34231288Antibacterial Activity of 2-Hydroxyisocaproic Acid (HICA) Against Obligate Anaerobic Bacterial Species Associated With Periodontal Disease. | Sakko, M., et al. 2021. Microbiol Insights. 14: 11786361211050086. PMID: 34707364Antibacterial efficacy and possible mechanism of action of 2-hydroxyisocaproic acid (HICA).3-Amino-5-chloropyrazine-2-carbaldehyde supplier | Pahalagedara, ASNW.2369772-11-0 Chemscene , et al.PMID:33388784 2022. PLoS One. 17: e0266406. PMID: 35363830Unique Probiotic Properties and Bioactive Metabolites of Saccharomyces boulardii. | Fu, J., et al. 2022. Probiotics Antimicrob Proteins.. PMID: 35608794Evaluation of the removal of 2-Hydroxyisocaproic acid from the root canal and its effect on the bond strength of MTA. | Usta, SN., et al. 2022. Aust Endod J.. PMID: 35852919Hydroxy acid metabolites of branched-chain amino acids in amniotic fluid. | Jakobs, C., et al. 1984. Clin Chim Acta. 140: 157-66. PMID: 6467607Studies of urinary organic acid profiles of a patient with dihydrolipoyl dehydrogenase deficiency. | Kuhara, T., et al. 1983. Clin Chim Acta. 133: 133-40. PMID: 6688766