Product Name :
WDR77 Recombinant Rabbit Monoclonal Antibody [PSH0-07]
Predicted band size :
37 kDa
Observed band size :
40 kDa
Synonyms:
2610312E17Rik antibody Androgen receptor cofactor p44 antibody C79984 antibody HKMT1069 antibody MEP 50 antibody MEP-50 antibody MEP50 antibody MEP50_HUMAN antibody Methylosome protein 50 antibody MGC2722 antibody 展开
Function :
Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human WDR77 aa 1-342 / 342.
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
PSH0-07
RRID:
AB_3072377
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.5-Methoxypicolinimidamide hydrochloride custom synthesis Aliquot store at -20℃.Formula of 5-Chloro-4H-1,2,4-triazol-3-amine Avoid repeated freeze / thaw cycles.PMID:33427425
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 37 kDa
Positive control :
Human prostate tissue, human fallopian tube tissue, mouse brain tissue, HepG2 cell lysate, 293 cell lysate, K562 cell lysate, Hela, HepG2.