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Health and fitness hazards attributable to diet regime happen to be evaluated by each epidemiology and biological techniques. Epidemiology, having said that, has poor resolution in the chemical degree. For example, though screening of food items and individual chemical substances for nucleotide mutagens is effective making use of the Ames assay, screening for clastogens is inefficient and has employed a number of cell- and animal-based assays.?2013 Elsevier Ltd. All rights reserved. Corresponding author: Dr. Scott E. Kern, Key: 410-614-3314, Fax: 443-287-4653, [email protected]. Publisher’s Disclaimer: It is a PDF file of an unedited manuscript which has been accepted for publication. As being a service to our prospects we’re providing this early model of the manuscript. The manuscript will undergo copyediting, typesetting, and evaluation with the resulting.