Product Name :
PFKFB2/PFK2 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 2 antibody 6-bisphosphatase antibody 6-P2ase 2 antibody 6-P2ASE heart-type isozyme antibody 6PF 2 K/Fru 2 6 P2ASE heart type isozyme antibody 6PF-2-K/Fru-2 antibody 6PF-2-K/Fru-26-P2ase 2 antibody 6PF-2-K/Fru-26-P2ase heart-type isozyme antibody F262_HUMAN antibody Fructose 2 6 bisphosphatase cardiac isozyme antibody 展开
Function :
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 is an enzyme that in humans is encoded by the PFKFB2 gene. The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. PFKFB2 has been shown to interact with YWHAQ.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human PFKFB2 51-150/505
Species reactivity:
Human, Mouse, Rat, Chicken, Dog
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1-Formyladamantane manufacturer Avoid repeated freeze/thaw cycles.4,6-Dichloro-5-nitropicolinic acid Order The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33645897 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
58 KDa
Positive control :
Heart.